Output you excell data to a comma delimited text file and then look at the documentation for the LOAD DATA INFILE command
It would look something like this
LOAD DATA
INFILE "/path/filename" INTO TABLE tablename
FIELDS TERMINATED BY ',' IGNORE 1 LINES
(field1, field2, field3, field4 );
This would be much easier than the previous suggestion, although that will probably work also.