It depends on many factors:
Is it a dedicated or virtual server?
Is the DBMS on the same server or a dedicated box?
How much horsepower is in these boxes?
I have entirely dynamic sites, ones that retrieve every aspect of each page from a DB. With these OO designs, that means 20+ DB queries per page view, minimum. Some of these sites get 5-6 thousand page views per day with no problem. Most of them run on a shared server, too.
I don't know about MySQL, but Apache + PostgreSQL + PHP handles it like a champ with everything, including POP/SMTP all on the same box.
My recommendation, concentrate on a good, maintainable design that meets the application requirements. You can always seperate the DBMS to it's own server if necessary and horsepower is cheep. A good, maintainable design will save you far more money in the long run.
my $0.02
-- Rich