The great thing about EditPlus is, if your server isn't on your local machine, you can FTP in and edit them directly off the server. Saving the file automatically uploads the new version of the file.
EditPlus also has syntax highlighting which many people believe is a cheat at code. I believe all it does it make it easier for you to spot your mistakes (I do not use auto completion, though EditPlus supports it).
Most people swear by notepad because it gives you complete control. EditPlus does not take any control away from you, it makes your whole development experience less about the little things (debugging your code for hours until you find that " that you somehow didn't type, uploading the files yourself) and more about the actual code (which for me ends up being easier to read with the highlighting).
The way I see if, if you want to use NotePad, power to you. Hell, if you want to use Frontpage, that's your choice. Personally, I'd never even think about loading up the program, (I don't even install it when I install MS Office). But just because I use EditPlus, or someone uses UltraEdit (another popular one that is simiilar in features to EditPlus) then that doesn't mean we are any less of a programmer.
Use what you want, and then just smile and nod when people start ranting about Notepad. 😃
--kinadian