The simplest thing to do is to save your Excel sheet as a tabbed text file.
So, if you have an Excel sheet with the following items:
id name age
1 Jim 30
You will have a test file with these same elements, only with tabs between then.
You can then load that into your tables using something like the following:
load data local infile '/path/to/your/tabbed/file' into table YOUR_TABLE (id, name, age);
Assumes YOUR_TABLE has fields of 'id', 'name' and 'age.'
That will import the file, creating one record for each line in the tabbed file.
Hope this helps.
-- Jason