Posting against the same record at the same exact time... not likely to happen. One user will get to the record first, it will be locked so others can't get to it until the first user is finishes.
I don't think you have to worry about the above happening. No site that is using mySQL would have to worry about this since the majority of them are small sites when compared to ebay... amazon and the like.
You should consider using transaction logic if you're update or write requires multiple SQL executions.