sure. $_POST['email'] is referring to variable email coming from a form with a method of post. That means
<form method="post" action="bla.php">
<input type="text" name="email">
</form>
I could use $email to access the form variable, but for most servers (depending on how they're configured) to access $email, you'd need to use $_POST['email']
Same with anything in the URL (which would be a method of GET)
if your url looked like this www.yourdomain.com/index.php?p=whatever
to access variable p, you could use $p (if globals were set to on in your settings), but most servers require you to use $GET['p'] ($GET and $_POST are both globals)
Hope this made sense.
Cgraz