Note that the mail() function is not actually doing anything in this case, mail() is just for sending mail.
Another option ( if you are sending HTML email ) is to embed an image in the email... something like:
<img src="http://www.MyDomain.com/MyScript.php?email=ThisPersonsEmail@TheirDomain.com" />
Then, make that PHP script record each access to that 'image' ( make it is an image by fpassthru() or readfile() and image, and make sure you send the correct Content-type header() ), and then you can pretty much assume, anyone who saw the image will have seen the rest of your eamil too :-)