hello,
Where do you plan to transfer the information? On the same network or a remote server.. and via what protocol? FTP, SMB, NFS?
Here is the easy part..
If you have a large database like this i assume that you have shell access of a method of getting a script to run via "crond".
I would create a shell script that runs "mysqldump" compresses the database backup (possibly splits the compresses files for transfer).
Once this is complete you would implements something to move the files to the remote machine.. via FTP, SMB or NFS..
thanks,
- justin