Hi
A bit more info may be helpful.
Is this under test conditons on your on pc as a local server, or over the internet?
Does the page have any java/dhtml (if so, especially if it writes to objects on the page)?
From a cold boot, run the test page, observe the title bar of IE. Do the fonts suddenly get smaller at any stage?
Do you have an application that shows how low on system resources you are when it happens?
I have a freeware find/replace package (actually it is quite good, coz it looks like a search (like google) engine is use) called InfoRapid Search and Replace, and that has a warning bar that gives you an idea how stretched windows is.
IE DOES have a memory leak, which can be quite bad depending on what you are doing, which eventually causes it to go t*ts up.
Trevor