Hrm, Sendmail has a SMART_HOST define (or something like that), but I'm not sure exactly what it does. I think that basically it acts like a local MTA, but actually connects to the ISP's mailserver to do the real work.
Depending on what you're trying to do, (you mentioned "mass emailers" :eek: ), it might be something to read up on.
Assuming, of course, that you're using Sendmail. Probably Postfix has something like this, too..
[edit]Of course, after I posted I noted that you'd said you're a Windoze user. Personally, I do very little on Windoze except gaming and fixing many broken ones.... However, if the technology is available to good ole King James Sendmail, then it's likely there are a few MTA's that could do similar things for Windoze, and you might even find one at SourceForge for free, etc., etc...[/edit]