Bear in mind that it is also going to find numbers 122, 226, 1221 etc.
My guess is that you either need to control the data entry VERY strictly to enable an exclusive search for LIKE '22,%' OR LIKE '%, 22,%' to only get 22 (even if it is the first entry).
Also guessing: this column related records in this table to those in another table in a Many to Many relationship: a common newbie solution. What you should have is a seperate table that relates the 2 tables.
field_id, number
1 , 22
1 , 12
2 , 9
3 , 11
2 , 22
2 , 14
1 , 19
3 , 6
3 , 88