Most likely that's how they do it. In you .htaccess file (web root):
RewriteEngine on
RewriteBase /
RewriteRule ^.htaccess$ - [F]
RewriteRule ^([a-zA-Z0-9\._-]+)/?$ page.php?name=$1
This will give you the same effect as what you see in the MySpace URI. Of course, you want to change page.php to whatever you page name is, and always do proper validation and escaping whenever dealing with user input (what-if they just try page.php?name=fill_in_your_attack_here)?
~Cameron