Because of the overhead of PHP, it is unlikely to be feasible to handle a 450,000 x 450,000 array natively.
If you really need to do this, consider using C++ instead. I am assuming that your system has enough RAM to do it (and probably 64-bit might be a good idea so you don't run short of address space).
Otherwise, consider an alternative approach.
PHP is generally a poor choice for high performance scientific computing due to its poor performance, weak typing system etc.
Mark