Well, there is something of a security risk to just include a file specified like that without validating the incoming variable. You may have a list of valid areas in an array, and check from there, e.g.,
$areas = array('home', 'foo', 'bar', 'baz');
if (isset($_REQUEST['area']) && in_array($_REQUEST['area'], $areas)) {
include 'content_includes/' . $_REQUEST['area'] . '.inc';
} else {
include 'content_includes/home.inc';
}
Incidentally, it is probably redundant to write empty($area) since the check should be for the incoming variable before it is used to initialise $area. Not only that, but isset($REQUEST['area']) && !empty($REQUEST['area']) would also contain redundancy since a variable that is not empty should always be set.