What are those "//" supposed to be? Anyway.. You can use $GET['NewsID'] (or any other variable) in many ways. For example:
$var='lorem ipsum '.$_GET['NewsID'].' lorem ipsum';
$var="lorem ipsum ".$_GET['NewsID']." lorem ipsum";
$var="lorem ipsum {$_GET['NewsID']} lorem upsum"; // Inside double quotes variables are parsed. Always use {$var}, not $var only
In your situation, I would use single quotes (the first version). Also althought its a windows system, use forwards slashes instead of backslashes.
$destination1 = 'c:/directory/you/want/to/save/to/pic_'.$_GET['NewsID'].'.jpg';
Also if $GET['NewsID'] is supposed to be numeric, make sure it is. Never trust content coming from $GET, $POST,$COOKIE or $_REQUEST. I know that you are using this on local server but its better to make it right from the beginning.