Which ID, the row or the item?
How about:
SELECT * FROM store_item_size
GROUP by item_size
Now, your questions seem to be incorrect. If indeed you need 2 rows, then you'll add
LIMIT 2.
SELECT * FROM store_item_size
GROUP by item_size
LIMIT 2
If what you meant two columns, then
SELECT item_size, item_id FROM store_item_size
GROUP by item_size