First off, you have a problem with your loop structure
# do-while is run once before while condition is checked
do
{
# so $row_rsMedia is not defined here (unless you place a call to mysql_fetch_assoc
# BEFORE the loop)
$acknow[] = $row_rsMedia['con_Acknow'];
} while ($row_rsMedia = mysql_fetch_assoc($rsMedia));
But a better solution is to run a while loop, for which the while condition is evaluated before the loop is run even once
while ($row_rsMedia = mysql_fetch_assoc($rsMedia))
{
$acknow[] = $row_rsMedia['con_Acknow'];
}
Now, let's say the call to implode creates the string "1, 2, 3", and for this to be a link you need <a href="...">1, 2, 3.</a>. So, you either need to include the link stuff "<a href...>" and </a> in the same echo statement, or in separate echo statements just before and just after the echo of "1, 2, 3."
echo '<a href="http://example.com">'.implode(", ", $acknow). ".</a>";